Iso-Accutane (Isotretinoin) is a medication that belongs to the class of drugs called retinoids and is used to treat severe acne (nodular or cystic acne) that has not improved with other treatments. It works by decreasing the production of oil in the skin and helping to unclog pores. Iso-Accutane comes in tablet form and each tablet contains 20mg of Isotretinoin. It is usually taken once or twice daily and should be taken with food. Common side effects include dry lips, nosebleeds, and skin irritation.